Over the past 50 years various new delivery systems were refined for administering drugs, hormones and latterly nutritional supplements.
Where possible, the preferred route would be oral (by mouth) administration.
Another, diffusional pathway could be employed by “Pessary” or “suppository”.
Subcutaneous deliveries could be made by creams, ointments and gels and even by oral spray/mist via endothelial tissue in the mouth. The latter providing a very short and effective pathway to the brain.
Even though “Enteric” coating of tablets and capsules does
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